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There are other non-microbes present such as bacteria, fungi, and viruses that can also cause problems to the vagina. Bacteria consist of only a single cell but are amazingly complex.

Bacteria have also been found that can live in temperatures above boiling point and well below freezing temperatures. They "eat" everything from sugar and starch to sunlight, sulfur, and iron.

Bacteria have fallen into a category of life known as the Prokaryotes. Moreover, Prokaryotes' genetic material, or DNA, is not enclosed in a cellular compartment called the nucleus.

Bacteria along with their microbial cousins the archaea were the earliest forms of life on Earth. They have played a vital role in shaping our planet into one that could support the larger forms of life through the process of photosynthesis.

A great example of bacteria in the vagina is Bacterial vaginitis which results in a vaginal discharge.

Bacterial vaginitis is caused by bacteria and treatment is usually with antibiotics [24]. Fungi are eukaryotic organisms and their DNA is enclosed in a nucleus.

Fungi are said to be "plant like", but fungi do not make their own food from sunlight like plants do. Fungi are very useful to humans as they have helped make antibiotics to fight bacterial infections.

Fungi come in a variety of shapes, sizes, and different types. They can range from enormous chains of cells that can stretch for miles or single individual cells.

An example of a fungal infection to the vagina would be a Fungal Yeast Infection [24]. A virus is a small bundle of genetic material DNA or RNA that is carried in a shell called the viral coat, or capsid, which is made up of bits of protein called capsomeres.

However, viruses cannot metabolize nutrients, produce and excrete wastes, move around their own, or even reproduce unless they are inside another organism's cells.

Ultimately, viruses are not even cells yet they have played key roles in shaping the history of life on our planet by shuffling and redistributing genes in and among organisms and by causing diseases in animals and plants.

A perfect example of viruses in the vagina is Viral vaginitis that can be caused by herpes simplex virus that is spread by sexual intercourse [24].

Now do you have a better understanding of how complex the vagina can be? Conditions of the human vagina differ with changes in life stages menstrual cycle, pregnancy, and menopause.

As conditions change, colonization by microbes commonly found in the vagina also change which can lead to harmful diseases such as bacterial vaginosis and B-streptococcus infections.

As you can see, altering the vaginal environment can lead to certain consequences. Thus, it is very important to keep pro-biotic microbes such as Lactobacillus acidophilus present in the vaginal environment because they act to inhibit other microbes that may be harmful to us and even our babies.

So remember to eat lots of pro-biotic foods such as yogurts and cheeses to help keep a healthy and infection fighting vagina! Research is still being done to try and figure out more about this microbe niche.

Below are a few articles that include: the differing compositions of the vagina in Caucasian and African American women, antibiotic effects on microbes, vaginal conditions during pregnancy, and more.

Prior studies have shown that anaerobic bacterium, Atopobium vaginae had been closely related with Bacterial vaginosis. There have only been four isolates of this fastidious organism that were found to be highly resistant to metroniadazole and susceptible for clindamycin , two antibiotics preferred for the treatment of Bacterial vaginosis.

The research group studied the susceptibility of nine other A. The decided method for this particular research involved nine strains of Atopobium vagina , four strains of Gardenerella vaginalis , two strains of Lactobacillus iners and one strain each of Bifidobacterium breve , B.

Longum , L. Crispatus , L. The conclusion of this research had shown Clindamycin had a higher activity against Gardenerella vaginalis and A.

In addition, the research group had concluded Bacterial vaginosis as a polymicrobial disease and the organisms that were involved were likely to be in a symbiotic relationship to each other for various metabolic requirements.

In conclusion, clindamycin was shown to dimish the vaginal colonisation resistancere. However, resistance to clindamycin seems to develop more readily than resistance to metronidazole which becomes apparent from clinical studies comparing both antibiotics.

Future studies will focus on determining the antibiotic suseptibility of the vaginal specie that will shed light to develop new regimens for treatment of recurrent bacterial vaginosis.

An important note is to make clear whther this metronidazole resistance might be acquired by the presence and activation of nim-genes [25].

In essence, all females vagina have the same construct. But the question is whether or not race plays a role. In , researchers from the Department of Biological Sciences at University of Idaho conducted a study to see if and how differences in bacterial communities in the vagina differ from Caucasian and Black women; and how these variations could lead to possible infections.

The hypothesis was that there indeed are differences in the composition as well as structure of bacterial colonies the vaginas of Caucasian and Black North Americans.

In this study, Caucasian and Black women from North America who were healthy, menstruating, not pregnant but are capable of becoming pregnant, and are within the reproductive age, had samples taken near the middle of their vaginas with a sterile swab.

These samples were then analyzed. Depending on the similarities of the composition of the communities, different bacteria were divided into groups called supergroups.

The results from this experiment concluded that the kinds of microbes found in the vaginas of Caucasian women and Black women were very different.

They found it super suprising that supergroup III, which included communities of Atopobium sp and other anaerobes, were four times as common in Black women as Caucasian.

Overall, the hypothesis that there are differences in the composition as well as structure of bacterial colonies the vaginas of Caucasian and Black North Americans proved true.

Researches did not stop after they adequately proved this hypothesis. Recently, studies have been conducted on the appearance of Atopobium in the vaginal of women in their reproductive age and postmenopausal women.

From their findings, it suggests that Atopobium is a common vaginal microbe in all healthy women [26]. Scientists isolated Lactobacillus helveticus , strain DPC, from swiss cheese and explored its relationship and similarities with non-dairy lactobacillus strains found in the human GI tract,; specifically Lactobacillus acidophilus strain NCFN.

NCFN also has half the amount of PTS system, membrane protiens cell wall adherence proteins , and sugar metabolism compared to DPC due to selective deletions in the genome.

Sources of such deletions are results of point mutations, horizontal gene transfers and transposons. Such genome differences between the strains provide significant scientific insight into gene roles in pro-biotic genomes and identification of niche-specific genes [27].

Changes in the Predominant Human Lactobacillus flora during in vitro fertilisation The research done by these Swedish scientists was to characterize the normal cultivable vaginal Lactobacillus flora at varying estradiol levels in plasma.

The use of signature matching of nucleotide sequences in the V1 and V3 regions 16S rRNA genes using pyrosequencing technology is a great way for locating vaginal Lactobacilli on the species level and learning more about the vaginal microbial niche.

The study was comprised of 17 patients who unerwent ovarian stimulation for In Vitro Fertilization IVF whose vaginal status was determined "normal" according to the Ansel and Nugent criteria.

The results of this study showed that 7 out of 10 patients had traces of L. In addition, the remaining 3 women's flora were dominated by L.

Rhamnosus or L. However, as their estrogen levels began to rise their flora composition was altered and became dominated by one of the three species that were most common in a healthy vagina.

Future studies on this topic should focus on signature matching of nucleotide sequences in the V1 and V3 regions of 16S rRNA genes.

This is a discriminative tool for the study of vaginal lactobacilli and can be used to track the Lactobacillus flora under a wide range of physiological conditions [28].

The purpose of this study was to determine what vaginal characteristics could lead to premature delivery of infants. The vaginal pH and Gram Stain Score was determined and recorded for all women leading to a recorded birth.

Results showed that women with a pH of 5. They also found that there was fewer spontaneous preterm births in women whose pH was 5.

Also with the women with pH 5. The results of the Gram Stain Scores supported the results shown by the vaginal pH experiments.

Women with a pH of 4. Those with Gram Stain Scores of 0 to 8 were at a lower risk of preterm birth. Another conclusion pointed out in this study concluded that making alterations to normal vaginal flora is associated with a 2-fold increase in a woman's risk of premature delivery.

In summary, disruptions of the normal vaginal flora were able to be determined by looking at a pregnant woman's vaginal pH and Gram Stain Score changes.

Further studies related to this topic can help us reach a firm conclusion of how we can utilize Gram Stain Scores to help diagnose Bacterial Vaginosis.

It is said that women afflicted with Bacterial Vaginosis show Gram Stain Scores ranging from 0 all the way to Although Gram Stain Scores and vaginal pH are reliable indicators of a woman's risk for preterm birth, they are not for Bacterial Vaginosis [29].

Volume 4 Number 4. April Antonio, Stephen E. Hawes, and Sharon L. The Journal of Infectious Diseases , Characterisation and selection of a Lactobacillus species to re-colonise the vagina of women with recurrent bacterial vaginosis J.

Sha, M. Reza Zariffard, Qiong J. Wang, Hua Y. Chen, James Bremer, Mardge H. Cohen, and Gregory T. Urology Channel. Group B streptococci and vaginal discharge.

PubMed Central. Antibiotic susceptibility of Atopobium vaginae. BMC Infect Dis. Published online March Brown, Zaid Abdo, Catherine C. Davis, Melanie A.

Hansmann, Paul Joyce, James A. Foster and Larry J. Differences in the Composition of vaginal microbial communities found in healthy Cacuasian and Black Women.

Fitzgerald, G. Journal of Bacteriology, January , p. Changes in the predominant human Lactobacillus flora during in vitro fertilisation.

Early pregnancy threshold vaginal pH and Gram stain scores predictive of subsequent preterm birth in asymptomatic women American Journal of Obstetrics and Gynecology, 3 , pp.

From MicrobeWiki, the student-edited microbiology resource. Jump to: navigation , search. This is a curated page.

Report corrections to Microbewiki. Category : Curated Pages. Personal tools Log in. A tightly packed accumulation of pus near the anus which can be extremely painful.

This type of anal infection most commonly arises from bacterial or intestinal debris contaminate the anal gland which creates an infection underneath the skin.

Moreover, Anal Abscess can spread bacteria and unwanted microbes to the vagina because of their close proximity's and can infections around or inside the vagina [7].

A linear crack or tear in the skin of the anus which can spread all the way to the vagina if serious. This most commonly occurs when a massive, hard stool over-stretches the anal opening and tears the delicate skin between the anus and vagina.

Anal Fissures also exposure the underlying muscles between the anus and vagina and unwanted microbes can enter open wounds and increase the chances of infections around the vagina [7].

At the beginning of a woman's menstrual cycle, vaginal discharge will seem sticky. Prior to ovulation, the amount of discharge increases and becomes very wet or runny.

On the day of ovulation, the most discharge is being produced and secreted. After ovulation, the discharge becomes thicker and the amount gradually decreases [9].

During pregnancy, a woman's body will produce more estrogen and progesterone than normal and will trigger an increase in vaginal secretions.

Most of this increase in volume is geared toward the growing fetus in the uterus. There isn't really any such thing as a "vaginal seal".

Some women have a hymen, a thin membrane near the vaginal opening that sometimes seems like an obstacle. Normally it is just a partial flap of skin, and does not completely block the vagina.

More often than skinny women, but many like thin men. It can vary considerably. Every one has her own preference. Some women prefer thin, average and some prefer fat guys.

Women tend to look more at the personality than just the visual cues like men do. It can be painful when your hymen tears, but the only bad thing that can happen is that you bleed a little bit just like you would at the end of your period.

Yes, however it also depends on the BMI of the individual. In generic terms, men do eat faster than women because men have higher energy needs.

However, a heavier person will eat faster than a thin person regardless of gender. The vagina should always be moist.

That is to protect itself against bacteria. The discharge leads the bacteria out of the vaginal canal. At certain times in the cycle there might be more and some use thin pads in their underwear.

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